FillCell – Filling cell and gene therapeutics

About this product

Safety to maximum yield You want to fill your sensitive gene and cell therapeutics flexibly, fully controlled, and with zero product loss. For Fill & Finish, Optima Pharma offers FillCell, a wide range of filling systems for all therapeutic applications and container types. We adapt the machine concept to your product. Integrated product saving features prevent product loss. For you, this means maximum yield and cost efficiency. Robot technology makes FillCell filling lines highly flexible, and systems for rapid decontamination ensure economical and safe processes. Your benefits: A highly-flexible system and robotics platform 100 % inprocesscontrol Technologies maximize product yield Proven isolatortechnology ensures safety Containment compatible for BSL 2 FillCell – Filling for cell and gene therapy What should your FillCell filling solution for cell and gene therapeutics look like? That depends on your product. We define the best feeding process depending on the container required. Maximum product yield and cost efficiency during filling and closing are ensured by sophisticated functions for redosing, restoppering, and recapping, as well as 100% process control. An overview of the process steps for filling cell and gene therapeutics 1. Feed 2. Filling 3. Closing 4. Discharge 1. Feed First, vial feeding takes place. The object feeder is also designed to process specific vials for cryopreservation. 2. Filling We precisely match filling and dosing technology to each product, which means you can rely on gentle and precise handling. Integrated functions ensure maximum product yield. 3. Closing The vials are usually closed by plugging and crimping. In this context, product saving features also prevent product losses. 4. Discharge When the process is complete, the filled and sealed vials are magazined and discharged. Automated for maximum filling flexibility Isolator The compact, BSL-2 compatible isolator with DECOpulse decontamination system promises maximum safety for both products and operating personnel. Your advantage: short cycle times combined with reliable decontamination (this is ensured by uniform moistening of the inner surfaces with vaporized H2O2). Distinguished with the Biotech Award. Turnkey approach The filling machine with isolator from a single manufacturer, in combination with the CSPE approach, simplifies your project handling. Prior to delivery, we commission your system and test it in all respects. This allows you to start production safely and immediately. Mobile glove testing system With the mobile glove testing system, you perform the leak test for gloves automatically – reliable, flexible, and easy to use. Robotics The use of robots enables a maximally flexible system and an automated, replicable production sequence. This increases your safety and reduces the workload of your staff. 100 percent in-process controls In-process controls guarantee both product and process safety as well as maximum product yield and the resulting cost efficiency. For example, you can activate a one hundred percent weight control plus redosing function during the filling process. In combination, both functions ensure that the intended filling quantity is reached. Product recovery Comprehensive product saving functions (e.g. redosing, restopping, recapping) minimize rejects, thus enabling you to fully utilize the available amount of product.