ProCell – Solutions for production

About this product

Manufacturing cell and gene therapeutics involves multiple process steps that often take days and weeks to complete. You determine the degree of automation: The ProCell production platform allows everything from manual work in the isolator to fully automated expansion stages. Your benefits: Modular machine design enables individual combination of processes High process, product and staff safety Operator and product kept completely separate thanks to isolator technology Process automation and automated batch recording possible Adaptable process steps for production Manufacture different products with the same system Production process steps for cell and gene therapy The many production steps include upstream and downstream processes. Upstream processes include cell selection, genetic modification, and cell proliferation, among others. Downstream processes include purification and the final formulation of cell and gene therapeutics. With a production platform like ProCell, you always have an overview of all process steps. Thanks to isolator technology, the operator and product remain safely separated from each other. Intelligent software accompanies the process and enables its automation. Optima Pharma's ProCell production isolators are modular in design. In concrete terms, this means you can create open and closed production areas, define the process sequence individually, integrate different devices and process steps, or use the option to scale out. Tailor the automation of your processes Isolator The compact, BSL-2 compliant isolator with a decontamination system promises maximum safety for products as well as operating personnel and reduces the surrounding cleanroom class. It was awarded the Biotech Award. HMI The fully integrated HMI with modular software structure documents processes in an automated and GMP-compliant manner. The fully automatic control system is adaptable within the approved scope. Another plus: You can combine digital solutions such as augmented reality glasses with the HMI. Automation Inside the isolator, automated control units and robot technology ensure maximally flexible, repeatable processes with no need for human intervention. Centrifuge for cell separation, microscope or pipetting module Integrate various function modules for an individual sequence and flexible adaptation of your processes. Your advantage: You can manufacture and fill the cell and gene product in the system. In addition, your system can also manufacture several products simultaneously. Material transfer chamber and ports between a laminar flow unit and the isolator Enable fast and safe transfer of patient or consumable supplies and other preparatory work. ProCell OPTIMA pharma GmbH and its partners, Robert-Bosch-Hospital (RBK) in Stuttgart and Heidelberg University-Hospital (UKHD) are working on the first decentralized automated production facility for cell and gene therapeutics. State of Baden-Württemberg The “ProCell for Patient” project for the automated production of CAR-T cell therapies is required by the state of Baden-Württemberg. Forum for health and wellness The forum for health and wellness in Baden-Württemberg supports the “ProCell for Patient” project.