Solutions for syringes, cartridges and vials (RTU)

About this product

Ready, steady, OPTIMA Intelligent equipment for aseptic filling of ready-to-use containers in a nest Syringes, cartridges or vials : Filling and packaging pre-sterilized components in ready-to-use (RTU) containers requires specialized system technology. This is our core competence: From custom-fit syringe filling machines to complete turnkey solutions, including pharmaceutical isolators for your application. Rely on filling equipment that is as ready-to-use like your containers Time and cost in pharmaceutical developments are increasing. To help you start production feeling more confident and, above all, faster, we have developed CSPE (Comprehensive Scientific Process Engineering) and other intelligent end-to-end processes. Our mission: Accelerate your time to market, as well as your operational process times. We design system technology for your primary packaging and secondary processing, which are agile and precisely tailored to your needs, based on Optima’s technology platforms. Encompass all steps from filling and closing, including upstream and downstream processes: From nest removal to labeling, as well as the insertion of piston rods, assembly of safety devices, finger flanges and much more. Process steps for handling your RTU containers in the nest 1. De-bagging Whether your RTU packaging materials arrive single or double bagged at the filling line, you can choose a manual, semi-automatic or fully automatic system from our portfolio. Bags are opened to remove the tubs. The tubs are pushed out of the bag, without being touched and then transferred to the sterile area. Benefits: ● Unpacking of the tubs either manually, semi-automatically or fully automatically ● The tub is transported, to the next station, without being touched Multiple options for transfer to sterile area (single or double bag, E-Beam) 2. Remove Tyvek® film A robot specifically designed for use in the cleanroom removes the intermediate layer of Tyvek® film. Benefits: Sterile room compatible robot system Clear separation of cleanroom areas Compact and pharmaceutical grade design 3. Filling and closing Whether viscous or fluid: With the correct aseptic filling system, you can accurately fill any type of product – with either rotary piston pumps, peristaltic pumps or a time-pressure filling system. Solutions like single-use or CIP/SIP (cleaning-in-place/sterilization-in-place) for the filling path are available. Upon request, containers can be filled and closed under vacuum. No matter how you envision your system, together we will develop the optimal solution for you. No matter what you select, the design is compact, easily accessible and easy to operate. Benefits: Filling and closing of nested prefilled syringes, vials and cartridges Up to 60,000 pieces per hour Filling systems and filling paths to accommodate the product Application-friendly systems with integrated in-process control 4. Monitoring Short acronym, big effect: The SIRM (Syringe Inspection and Reject Machine) is an exceptionally safe inspection system for syringes, a crucial component of our syringe filling equipment. It uses a robot and several cameras to remove defective syringes or cartridges from the tub. It also verifies the stopper height of the objects. Benefits: Automated inspection of syringes or cartridges Discharge of individual objects Maximum security 5. Isolator Containment solutions including isolators complement our turnkey portfolio for filling RTU nested containers. Good to know: You can combine the isolators with any type of pharmaceutical equipment, as well as numerous process functions. 6. Secondary processing Do you need to process filled and closed RTU containers? Choose from the comprehensive machine portfolio for secondary processing: Solutions for labeling, inserting and assembling piston rods, backstops and safety devices. Syringe transport systems, buffer systems, denesters and renesters complete the syringe secondary-processing portfolio. Benefits: Large portfolio for secondary processing Compact systems for labeling and inserting piston rods Appropriate backstop and safety device assembly machines Syringes and buffer systems to meet your space requirements Everything from one manufacturer: Saving time and reducing interfaces Good to know Aseptic syringe, cartridge or vial filling: Applications from A to Z Start-ups, contract manufacturers and big pharma from biotech to pharmaceutical industries worldwide choose Optima. Our team develops and designs systems for filling products in R&D, clinical trials, production of small quantities, as well as commercial production of any batch size. We find solutions through our expertise, ingenuity and a holistic understanding of your value chain. The result: A highly accessible, flexible and process-reliable production. For example, complex turnkey systems from Optima Pharma can handle vaccine filling, highly-potent products, heparin, hyaluronic acid, biotech and biosimilar products, generics and veterinary products. Filling RTU containers The basics of flexibility The use of ready-to-use containers is increasing – with an Optima Pharma filling system, you remain flexible. Because you can use it to fill a wide range of products with different requirements, including pre-sterilized syringes, vials or cartridges. Technology with added value Benefits of safe processes Safety is everyone’s number one priority. With Optima, numerous in-production controls with sensors and camera systems monitor your processes and products. We also offer a wide range of inspection and control technologies for various processes. In each case, the objective is your top product quality. Intelligent support Digital perspective With Optima's digital solutions, you gain production transparency. In addition, you can identify optimization potential, increase system availability and receive quick support, if needed. Because of the IPAS (Intelligent Production Assistance Services), developed by Optima, you have direct access to assistance and a broad knowledge database at any time during the production process. The right system for every output of your ready-to-use packaging materials If you are seeking a suitable system to fill different formats of sterile products in ready-to-use packaging like syringes, vials, or cartridges, Optima can help. We provide solutions for every application and every batch size – small or large, R&D, clinical trials or commercial production. For high speed performance, we offer filling systems with a capacity of up to 60,000 pieces per hour, for filling sizes of up to 50 ml.